VOLUME 1, ISSUE 6, 2017

The Influence of Genetic Variance on Attention Deficit Hyper Activity Disorder

Authors: Naman Bharara

Published: November 10, 2017

Abstract
Genetics databases were reviewed to determine if there is a correlation between specific genes and the severity of attention deficit hyperactivity disorder (ADHD) because the condition affects the emotional, social, and academic performance of 2 to 18 % of children worldwide. Datasets from Gene Expression Omnibus Database were analyzed using Gene Spring software to compare gene variations and expressions between ADHD and non-affected individuals. Results showed an increase in the expression of CXCL8 and DDX6, while there was a decreased expression of RHOT1, RPS24, and TMEM59 in the ADHD patients. The differences in gene expressions of the genes suggests that the disorder may have genetic disorders.

Keywords: ADD, ADHD, CNVS, hyperactivity, disorder, hyperactive, attention deficit